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As for transcobalamin II deficiency, an observational case series of 30 patients revealed that IM administration of 1 mg of OH-Cbl or CN-Cbl weekly for a lifetime appears to be a suitable treatment regimen (Trakadis et al., 2014)

[PMID: 26900641]( Healton EB, Savage DG, Brust JC, Garrett TJ, Lindenbaum J

Slides were all dried overnight at room temperature in the dark and then stored long-term at +4C

After receiving parenteral vitamin B12, the patients appetite improved, and he gained 3 kg by the time of discharge

Pickart's group showed it attracted immune cells and endothelial cells to wound sites, stimulated nerve outgrowth, and increased the production of vascular endothelial growth factor (VEGF), which promotes new blood vessel formation